Baylor College of Medicine Receives An Additional $11 Million in State Cancer Funding

Jo-Carolyn Goode | 2/23/2015, 4:24 p.m.
Researchers in the NCI-designated Dan L. Duncan Cancer Center at Baylor College of Medicine have received nine new grants totaling ...
Dr. Kent Osborne, director of the Duncan Cancer Center at Baylor

HOUSTON – (Feb. 23, 2015) – Researchers in the NCI-designated Dan L. Duncan Cancer Center at Baylor College of Medicine have received nine new grants totaling $11.3 million – a majority focused on advancing research into pediatric cancer – in the latest round of funding awarded by the Cancer Prevention and Research Institute of Texas.

The newest grants bring Baylor’s total CPRIT funding to more than $140 million since the agency began awarding cancer research funding in January 2010.

“These awards are well deserved by the researchers as they are funding potentially ground breaking research that could be paradigm changing,” said Dr. Kent Osborne, director of the Duncan Cancer Center at Baylor.

Baylor received four new individual investigator research awards for cancer in children and adolescents including the following new projects:

“Developing new combinatory therapies for pediatric high grade glioma” to Dr.Xiao-Nan Li for $1,945,940. Li is an associate professor of pediatrics – oncology at Baylor and a member of the Texas Children’s Cancer Center.

“Genetic susceptibility to testicular germ cell tumors” to Dr. Jason Heaney for $1,406,791. Heaney is an assistant professor of molecular and human genetics at Baylor.

“Drug discovery and mechanistic studies of protein methylation targeting leukemia” to Dr. Yongcheng Song for $1,733,813. Song is an associate professor of pharmacology at Baylor.

“Personalized functionalization of pediatric high grade glioma” to Dr. Benjamin Deneen for $1,820,319. Deneen is an associate professor in the Center for Stem Cells and Regenerative Medicine at Baylor.

“CPRIT is funding cancer research that is transformational in nature,” said Dr. David Poplack, professor of pediatrics – hematology and oncology at Baylor and director of the Texas Children’s Cancer Center, a joint program of Baylor and Texas Children’s Hospital which serves as the pediatric cancer research program of the Duncan Cancer Center. “It is helping us increase our understanding of cancer and is moving us more rapidly to find innovative new therapies.”

Baylor received five individual investigator awards including:

“Understanding how NCOA6 suppresses endometrial cancer by inhibiting the Wnt/beta-catenin pathway” to Dr. Jianming Xu for $886,524. Xu is a professor of molecular and cellular biology at Baylor.

“The role of progesterone receptor in early stage breast cancer” to Dr. Dean Edwards for $864,661. Edwards is a professor of molecular and cellular biology and of pathology and immunology at Baylor.

“Broad shortening of 3’ UTRs in human cancers: methods, target genes and functional consequences” to Dr. Wei Li for $900,000. Li is an associate professor in the Duncan Cancer Center at Baylor.

“Effects of hormonal therapy on subclonal evolution of breast tumors with ESR1 mutations” to Dr. Suzanne Fuqua for $899,805. Fuqua is a professor in the Lester and Sue Smith Breast Center at Baylor.

SRC-2 driven “Metabolic Switch” in metastatic prostate cancer-prognostic and therapeutic implications to Dr. Arun Sreekumar for $900,000. Sreekumar is an associate professor of molecular and cellular biology at Baylor.

For more information, visit www.bcm.edu/news